In the 1800s, olive leaf was used to treat malaria.( Bruneton 1995, Chevallier 1996, Lee-Huang 2003, Weiss 1988) The leaves were worn by athletes in ancient Olympic Games, and the olive branch has traditionally been a symbol of peace. The olive tree was cultivated in Crete, where the leaves were used to clean wounds as early as 3500 BC. The leaves are gathered throughout the year.( Chevallier 1996, USDA 2022, Weiss 1988) History The small, leathery leaves are gray-green on top, and the undersides contain fine, white, scale-like hairs. Native to Mediterranean regions, olive trees are also cultivated in similar climate zones in the Americas. europaea) is an evergreen that grows to approximately 10 m in height. Moodiness and aggressive behavioral changes likely related to olive leaf extract (at a dose of 85 mg/kg) have been reported in an elderly woman. Patients with diabetes should be supervised carefully because of potential hypoglycemic effects. Olive leaf may enhance the hypotensive effect of blood pressure–lowering agents or other herbal products with blood pressure–lowering effects. Information regarding safety and efficacy during pregnancy and lactation is lacking. Caution may be warranted in hepatic disease. ContraindicationsĬontraindications have not been identified. Supplementation with olive leaf extract (equating to a daily dose of oleuropein 51.1 mg and hydroxytyrosol 9.7 mg) for 12 weeks was examined in a crossover study evaluating effects on insulin action and cardiovascular risk factors in men with a BMI of 28 (☒) kg/m 2.
Olive leaf extract trial#
One clinical trial in patients with stage 1 hypertension used an olive leaf extract dosage of 500 mg twice daily for 8 weeks.
Many commercial olive leaf and olive leaf extract preparations of varying strengths are available.
However, clinical trial data are lacking to recommend use for any indication. Clinical Overview UseĬlinical trials have been conducted to evaluate the anti-infective/antiviral, anti-inflammatory, antioxidant, and hematologic activities of olive leaf, as well as its possible roles in diabetes and cardiovascular conditions. Common Name(s): OLE, Olive leaf, Olive leaf extract
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